diff --git a/lib/std/os/windows.zig b/lib/std/os/windows.zig
index 9f8aa326a..02adf1a92 100644
--- a/lib/std/os/windows.zig
+++ b/lib/std/os/windows.zig
@@ -940,8 +940,13 @@ pub fn DeleteFile(sub_path_w: []const u16, options: DeleteFileOptions) DeleteFil
     }
     defer CloseHandle(tmp_handle);
 
+    // FileDispositionInformationEx (and therefore FILE_DISPOSITION_POSIX_SEMANTICS and FILE_DISPOSITION_IGNORE_READONLY_ATTRIBUTE)
+    // are only supported on NTFS filesystems, so the version check on its own is only a partial solution. To support non-NTFS filesystems
+    // like FAT32, we need to fallback to FileDispositionInformation if the usage of FileDispositionInformationEx gives
+    // us INVALID_PARAMETER.
+    var need_fallback = true;
     if (comptime builtin.target.os.version_range.windows.min.isAtLeast(.win10_rs1)) {
-        // Deletion with posix semantics.
+        // Deletion with posix semantics if the filesystem supports it.
         var info = FILE_DISPOSITION_INFORMATION_EX{
             .Flags = FILE_DISPOSITION_DELETE |
                 FILE_DISPOSITION_POSIX_SEMANTICS |
@@ -955,7 +960,14 @@ pub fn DeleteFile(sub_path_w: []const u16, options: DeleteFileOptions) DeleteFil
             @sizeOf(FILE_DISPOSITION_INFORMATION_EX),
             .FileDispositionInformationEx,
         );
-    } else {
+        switch (rc) {
+            // INVALID_PARAMETER here means that the filesystem does not support FileDispositionInformationEx
+            .INVALID_PARAMETER => {},
+            // For all other statuses, fall down to the switch below to handle them.
+            else => need_fallback = false,
+        }
+    }
+    if (need_fallback) {
         // Deletion with file pending semantics, which requires waiting or moving
         // files to get them removed (from here).
         var file_dispo = FILE_DISPOSITION_INFORMATION{